About
Enoch teaches Anatomy & Physiology as well as Advanced Physiology and the associated laboratory practical works at UW-Stout. Prior to enrolling in this institution, he worked as a Postdoctoral Research Associate at the State University of New York and Iowa State University.
In his native country, Ghana, he taught Human Physiology to Medical, Radiography, Sonography and Clinical Nutrition & Dietetics students at the University of Cape Coast. Also, he taught Pathology to the Clinical Nutrition & Dietetics students at the University of Cape Coast. Moreover, he functioned as an Adjunct Physiology lecturer at the Klintaps University College of Health and Allied Sciences and as Anatomy & Physiology Tutor at Afia Kobi Nurses Training College, after working within the Chemical Pathology Unit of the Komfo Anokye Teaching Hospital.
As part of his Teaching Philosophy, Enoch is of the opinion that the success of a student is largely dependent on the teacher. So, he uses vivid teaching methods and does his best to ensure that all his students understand his lessons.
Enoch integrates teaching with research and serves as a reviewer for several reputable journals.
Research Interest
Enoch’s research interest is in the field of female reproductive biology, specifically placenta development and pregnancy pathology. The placenta is a transient but a vital organ that is crucial for pregnancy establishment, maternal health, and fetal development. It is mainly composed of three trophoblast subtypes: cytotrophoblasts, syncytiotrophoblasts and extravillous trophoblasts.
Current evidence indicates that abnormal placenta development is associated with pregnancy complications such as preeclampsia, miscarriage, fetal growth restriction and still birth but the underlying mechanisms remain to be clarified. Also, the prevalence of these pregnancy complications is high. However, appropriate proactive therapeutic interventions against them are limited partly due to their mysterious pathophysiology.
His aim is to contribute to clarifying the mechanism of human placenta development, assessing the toxicological effects of environmental chemicals on placenta development, unravelling the pathophysiology of placenta-associated pregnancy complications, and identifying therapeutic targets, drugs, and biomarkers for the clinical management of pregnancy complications.
Selected Publications
- Adu-Gyamfi EA, Salamah J, Cheeran EA, Lee B-K. Bisphenol S moderately decreases the expression of syncytiotrophoblast marker genes and induces apoptosis in human trophoblast lineages. Environ Pollut 2024; 343:123259.
- Adu-Gyamfi, E. A., Lamptey, J., Chen, X. M., Li, F. F., Li, C., Ruan, L. L., ... & Ding, Y. B. (2021). Iodothyronine deiodinase 2 (DiO2) regulates trophoblast cell line cycle, invasion and apoptosis; and its downregulation is associated with early recurrent miscarriage. Placenta, 111, 54-68.
- Adu-Gyamfi EA, Cheeran EA, Salamah J, Enabulele DB, Tahir A, Lee B-K. Long non-coding RNAs: a summary of their roles in placenta development and pathology. Biol Reprod 2024:ioad179.
- Adu-Gyamfi, E. A., Rosenfeld, C. S., & Tuteja, G. (2022). The impact of bisphenol A on the placenta. Biology of Reproduction, 106(5), 826-834.
- Adu-Gyamfi, E. A., Czika, A., Liu, T. H., Gorleku, P. N., Fondjo, L. A., Djankpa, F. T., ... & Wang, Y. X. (2021). Ephrin and Eph receptor signaling in female reproductive physiology and pathology. Biology of Reproduction, 104(1), 71-82.
- Adu-Gyamfi, E. A., Djankpa, F. T., Nelson, W., Czika, A., Sah, S. K., Lamptey, J., & Wang, Y. X. (2020). Activin and inhibin signaling: From regulation of physiology to involvement in the pathology of the female reproductive system. Cytokine, 133, 155105.
- Kim, M., Adu-Gyamfi, E. A., Kim, J., & Lee, B. K. (2023). Super-enhancer-associated transcription factors collaboratively regulate trophoblast-active gene expression programs in human trophoblast stem cells. Nucleic Acids Research, gkad215.
- Lamptey, J., Li, F., Adu-Gyamfi, E. A., Chen, X. M., Czika, A., Otoo, A., ... & Ding, Y. B. (2021). Downregulation of fascin in the first trimester placental villi is associated with early recurrent miscarriage. Experimental Cell Research, 403(1), 112597.
- Lee, B. K., Salamah, J., Cheeran, E., & Adu-Gyamfi, E. A. (2024). Dynamic and distinct histone modifications facilitate human trophoblast lineage differentiation. Scientific Reports, 14(1), 4505.
- Ruan, L. L., Chen, M. X., Adu-Gyamfi, E. A., Geng, L. H., Fu, L. J., Wan, Q., & Ding, Y. B. (2023). Maternal Hepatitis B Virus Infection and Pregnancy Outcomes of Freeze-Thaw Embryo Transfer. JAMA Network Open, 6(7), e2323495-e2323495.