Faculty & Staff Profiles

Maleka-Hashmi_1

Maleka Hashmi

Biology

Office: 203 Jarvis Hall - Science Wing
Phone: 715/232-2268
Email: hashmim@uwstout.edu

Education

PhD, Physiology, University of Georgia, Athens, GA, 2006

MSc, Pharmacology, University of Bradford, Bradford, UK, 1997

BSc, Physiology, University of Liverpool, Liverpool, UK, 1993

Research Interests

Hypertension, Blood Vessels, S-nitrosothiols, Endothelial Cells

My research interests focus on the role of the endothelium in the pathology of hypertension. I am especially interested in S-nitrosothiols and how their mobilization within endothelial cells or lack thereof may contribute to hypertension. I use a variety of techniques in my lab such as histology, ultrastructural microscopy, molecular biology, in vivo and in vitro techniques.

Courses Taught

BIO 132 Introduction to Human Biology

BIO 362 Advanced Physiology

Publications:

Hashmi-Hill MP, Shields JP, Lewis THJ, Robertson TP, Lewis SJ.

Light and ultrastructural investigation of cytoplasmic vesicles in endothelial cells of the rat. For Am J Physiol.

Hashmi-Hill MP, Shields JP, Lewis THJ, Robertson TP, Lewis SJ.

Light and ultrastructural investigation of proteins necessary for vesicular exocytosis in endothelial cells of rat small arteries. For Am J Physiol.

Hashmi-Hill MP, Shields JP, Lewis THJ, Robertson TP, Lewis SJ.

Acetylcholine and hypoxia elicit vesicular exocytosis in endothelial cells of rat mesenteric and femoral arteries: An ultra-structural study. For Circ Res.

Hashmi-Hill MP, Shields JP, Lewis THJ, Robertson TP, Lewis SJ.

Ultra-structural evidence in endothelial cells that acetylcholine induces exocytosis of vesicular stores of S-nitrosothiols. For Circ Res.

Hashmi-Hill MP, Sandock K, Bates JN, Robertson TP, Lewis SJ.

Flavin adenine dinucleotide may release preformed stores of nitrosyl factors from the vascular endothelium of conscious rats.
J Cardiovasc Pharmacol. 2007 Aug;50(2):142-54.

Hashmi-Hill MP, Graves JE, Sandock K, Bates JN, Robertson TP, Lewis SJ.

Hemodynamic responses elicited by systemic injections of flavin adenine dinucleotide in anesthetized rats.
J Cardiovasc Pharmacol. 2007 Jul;50(1):94-102.

Lewis SJ, Travis MD, Hashmi-Hill MP, Sandock K, Robertson TP, Bates JN.

Differential effects of ouabain on the vasodilator actions of nitric oxide and S-nitrosothiols in vivo: relevance to the identity of EDRF/EDHF.
Vascul Pharmacol. 2006 Dec;45(6):383-94.

Lewis SJ, Hashmi-Hill MP, Owen JR, Sandock K, Robertson TP, Bates JN.

ACE inhibition restores the vasodilator potency of the endothelium-derived relaxing factor, L-S-nitrosocysteine, in conscious Spontaneously Hypertensive rats.
Vascul Pharmacol. 2006 Jun;44(6):491-507.

Lewis SJ, Hashmi-Hill MP, Owen JR, Sandock K, Robertson TP, Bates JN.

The vasodilator potency of the endothelium-derived relaxing factor, L-S-nitrosocysteine, is impaired in conscious spontaneously hypertensive rats.
Vascul Pharmacol. 2006 Jun;44(6):476-90.

Professional Membership:

American Heart Association
American Thoracic Society

Office Hours

MF- 12:20-2:20pm

W- 12:20-1:15pm